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RTICC 2013
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INTRODUCTION

Despite the significant progress made on cancer research during the last two decades, we still have the challenge of making an impact on the survival of cancer patients. In basic molecular oncology, this failure can be attributed to a number of historical problems associated to the type of research made in the field. Thus, most studies have been done at pre-clinical stages, a functional scenario that does not accurately reproduce the biological conditions faced by anti-cancer therapies in the context of fully developed primary tumor masses or metastasis. In addition, most of the research has been concentrated in the usual suspects and their direct downstream pathways. Such approach has limited the identification of alternative, unorthodox routes engaged by nodal oncogenic molecules. The search for drugs also faced a similar “spinning wheel” situation, thus limiting the therapeutic avenues that could be explored to interfere critical regulatory molecules of the tumorigenic process. Finally, there have been obvious gaps in the understanding of all the molecular alterations that contribute to cancer, a problem that is being solved by current international efforts to sequence the genomes of tumors. + more...

OBJECTIVES

INNOVATION AND TECHNOLOGY TRANSFER

SCIENTIFIC AND TECHNICAL COORDINATION

TECHNICAL PLATFORMS

ADDED VALUE TO BE OBTAINED FROM THE COOPERATIVE MMoC WORK

IMPACT AND TRANSFER

DISSEMINATION ACTIVITIES

EXPLOITATION OF RESULTS

SCHEME OF EVALUATION OF THE PROGRAMME

Introducción
Coordinador
Grupos
Work Packages
Publicaciones
Proyectos
Ensayos clínicos
Otros resultados
Agenda
Enlaces
Intranet
Noticias
03/03/2017 | Otras reuniones
13/11/2016 | Otras reuniones
Publicaciones
RD12/0036/0053
Adherence to capecitabine in preoperative treatment of stage II and III rectal cancer: do we need to worry?
Font R, Espinas JA, Layos L, Martinez Villacampa M, Capdevila J, Tobeña M, Pisa A, Pericay C, Lezcano C, Fort E, Cardona I, Berga N, Solà J, Borras JM
Ann Oncol  2017.  4.  831-835.  PMID: 28327898. 

RD12/0036/0053
Understanding variations in the use of hypofractionated radiotherapy and its specific indications for breast cancer: A mixed-methods study.
Prades J, Algara M, Espinàs JA, Farrús B, Arenas M, Reyes V, García-Reglero V, Cambra MJ, Rubio E, Anglada L, Eraso A, Pedro A, Fuentes-Raspall MJ, Tuset V, Solà J, Borras JM
Radiother Oncol  2017.  1.  22-28.  PMID: 28236538. 

RD12/0036/0053
Current developments in cancer care: including the patients' perspective-3rd European Roundtable Meeting (ERTM) June 17, 2016, Berlin, Germany.
Ortmann O, Rösler W, Helbig U, participants of the ERTM.
J Cancer Res Clin Oncol  2017.  4.  673-676.  PMID: 27988842. 

RD12/0036/0005
Snail1-expressing fibroblasts as a source of paracrine signals in colon cancer tumors
Herrera A, Herrera M, Alba-Castellón L, Silva J, García V, Loubat J, Alvarez-Cienfuegos A, García JM, Rodríguez R, Gil B, Citores MJ, Larriba MJ, Casal JI, García de Herreros A, Bonilla F, Peña C
  2014. 
Grupos colaboradores: RD12/0036/0005 , RD12/0036/0041

RD12/0036/0005
The Epithelial-to-Mesenchymal Transition (EMT), a Particular Case.
Cebrià-Costa JP, Millanes-Romero A, de Herreros AG, Peiró S
Mol Cell Oncol  2014.  2.  e960770.  PMID: 27308335. 

RD12/0036/0005
Snail1 controls cooperative cell plasticity during metastasis.
Baulida J
Oncoscience  2015.  11.  898-9.  PMID: 26697515. 

RD12/0036/0005
Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3.
Herranz N, Dave N, Millanes-Romero A, Pascual-Reguant L, Morey L, Díaz VM, Lórenz-Fonfría V, Gutierrez-Gallego R, Jerónimo C, Iturbide A, Di Croce L, García de Herreros A, Peiró S
FEBS J  2016.  23.  4263-4273.  PMID: 27735137. 

RD12/0036/0005
Pharmacological Approaches in an Experimental Model of Non-Small Cell Lung Cancer: Effects on Tumor Biology.
Mateu-Jimenez M, Fermoselle C, Rojo F, Mateu J, Peña R, Urtreger AJ, Diament MJ, Joffé ED, Pijuan L, Herreros AG, Barreiro E
Curr Pharm Des  2016.  34.  5300-5310.  PMID: 27339432. 
Grupos colaboradores: RD12/0036/0005 , RD12/0036/0051

RD12/0036/0005
Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis.
Alba-Castellón L, Olivera-Salguero R, Mestre-Farrera A, Peña R, Herrera M, Bonilla F, Casal JI, Baulida J, Peña C, García de Herreros A
Cancer Res  2016.  21.  6205-6217.  PMID: 27503928. 
Grupos colaboradores: RD12/0036/0005 , RD12/0036/0041

RD12/0036/0005
Antisense non-coding RNAs and regulation of gene transcription.
Beltran M, García de Herreros A
Transcription  2016.  2.  39-43.  PMID: 26985653. 

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